Palytoxin is one of the most potent coronary vasoconstrictors known, producing death by the iv route within minutes by diminishing the supply of oxygen to the myocardium. Tests in animals with a number of vasdilators showed that papaverine and isosorbid dinitrate are effective antidotes, but must be injected directly into the ventricle of the heart because of the speed of the action of the toxin. Toxin Dose Test Animal palytoxin 60 nanograms dog (iv) alltså 60 000 000 delar av ett gram krävs för att avliva en hund